A young child is extremely susceptible to infections by a wide range of bacteria. A genome sequencing test determines that the boy has an inactivating mutation in a single gene. What is the most-likely candidate for the mutated gene?

Question

Quizplus · Accepted Answer

Toll-like receptors are crucial for the innate immune system to recognize pathogens and initiate an immune response. A mutation here would impair the child's ability to respond to a wide range of bacterial infections.

A Young Child Is Extremely Susceptible to Infections by a Wide