Applying drugs that act as antagonists at the NMDA glutamate receptor before spatial learning occurs interferes with
A)both LTP and spatial memory acquisition.
B)neither LTP nor spatial memory acquisition.
C)LTP, but not with spatial memory acquisition.
D)spatial memory, but not with LTP.

Question

Applying drugs that act as antagonists at the NMDA glutamate receptor before spatial learning occurs interferes with​ 
A)both LTP and spatial memory acquisition. 
B)neither LTP nor spatial memory acquisition. 
C)LTP, but not with spatial memory acquisition. 
D)spatial memory, but not with LTP.

Quizplus · Accepted Answer

The NMDA receptor plays a crucial role in long-term potentiation (LTP) which is thought to be the cellular mechanism underlying learning and memory. Antagonists at the NMDA receptor can block the induction of LTP, and thus interfere with spatial memory acquisition.

Applying Drugs That Act as Antagonists at the NMDA Glutamate