According to research,people who are diagnosed with major depressive disorder may have

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Research has shown that people with major depressive disorder have abnormal patterns of cortisol release. Specifically, some individuals may have elevated levels of cortisol in the morning, while others may have reduced levels throughout the day. This dysregulation of the stress hormone may contribute to symptoms of depression. There is currently no evidence to suggest that individuals with major depressive disorder have consistently elevated levels of serotonin or reduced levels of glutamate or cortisol.

According to Research,people Who Are Diagnosed with Major Depressive Disorder