A meal high in protein has the highest thermic effect (approximately 20- 30 percent), probably because of the synthesis of body proteins after a protein meal.

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The thermic effect of food (TEF) is highest for protein because digesting, absorbing, and metabolizing protein requires more energy compared to fats and carbohydrates, leading to a higher energy expenditure of approximately 20-30 percent of the energy content of the protein consumed.

A Meal High in Protein Has the Highest Thermic Effect