What can you infer about high-molecular-weight proteins that cannot be transported into the nucleus?
A)They are foreign proteins.
B)They lack nuclear localization signals (NLS).
C)They are defective proteins.
D)They have been tagged for destruction.

Question

Quizplus · Accepted Answer

High-molecular-weight proteins that cannot be transported into the nucleus lack nuclear localization signals (NLS). NLS are necessary for proteins to be recognized and transported into the nucleus by the nuclear pore complex. Therefore, the absence of NLS would prevent their transport into the nucleus.

What Can You Infer About High-Molecular-Weight Proteins That Cannot Be