Canine Phosphofructokinase (PFK)deficiency Afflicts Springer Spaniels,affecting an Estimated 10% of the Breed.PFK

Canine phosphofructokinase (PFK) deficiency afflicts springer spaniels,affecting an estimated 10% of the breed.PFK is the glycolytic enzyme that phosphorylates fructose-1-phosphate and catalyzes the committed step in glycolysis.Given its critical role in glycolysis,one implication of the genetic defect resulting in PFK deficiency in dogs is

A) early embryonic mortality.
B) elevated blood-glucose levels.
C) exercise intolerance.
D) nothing.It would have no visible effect on the health of the animal.