In humans, sex-chromosome aneuploids are more common than autosomal aneuploids. X-chromosome inactivation prevents problems of gene dosage for X-linked genes. Down syndrome results from three functional copies of chromosome 21, either through trisomy (primary Down syndrome) or a Robertsonian translocation (familial Down syndrome).
-Briefly explain why, in humans and mammals, sex-chromosome aneuploids are more common than autosomal aneuploids?

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The Answer of In humans, sex-chromosome aneuploids are more common than autosomal aneuploids. X-chromosome inactivation prevents problems of gene dosage for X-linked genes. Down syndrome results from three functional copies of chromosome 21, either through trisomy (primary Down syndrome) or a Robertsonian translocation (familial Down syndrome).
-Briefly explain why, in humans and mammals, sex-chromosome aneuploids are more common than autosomal aneuploids?

In Humans, Sex-Chromosome Aneuploids Are More Common Than Autosomal Aneuploids