Many tumors contain a variety of types of chromosome mutations. Some tumors are associated with specific deletions, inversions, and translocations. Deletions can eliminate or inactivate genes that control the cell cycle; inversions and translocations can cause breaks in genes that suppress tumors, fuse genes to produce cancer-causing proteins, or move genes to new locations, where they are under the influence of different regulatory sequences.
-Chronic myelogenous leukemia is usually associated with which type of chromosome rearrangement?

Question

Quizplus · Accepted Answer

Chronic myelogenous leukemia is commonly associated with a specific translocation known as the Philadelphia chromosome, which involves a translocation between chromosomes 9 and 22.

Many Tumors Contain a Variety of Types of Chromosome Mutations