A Florist Presents with a Subcutaneous Lesion on the Hand

A florist presents with a subcutaneous lesion on the hand, which she thinks resulted from a jab wound she received while she was making a sphagnum moss-wire frame for a floral wreath. The nodule has ulcerated and not healed despite use of antibacterial cream, and a new nodule is forming above the original lesion. What is most likely to be an appropriate treatment for this infection?

A) Oral itraconazole or potassium iodide
B) Miconazole cream
C) Cortisone cream
D) Oral griseofulvin
E) Penicillin