If one were to create a single antigen vaccine to have prevented the outbreak and for use as a vaccine in women prior to pregnancy, what viral molecule would be most likely to lead to the production of successful neutralizing antibodies?

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Quizplus · Accepted Answer

The disease is most probably erythema infectiosum (slapped cheek syndrome) caused by parvovirus B19, a single-stranded DNA virus. Parvovirus B19 is naked, so protective neutralizing antibodies would be to the viral capsid. It does not carry a polymerase but uses cellular polymerases, which is why it requires replicating cells. It is not enveloped, so it has no glycoproteins or any matrix proteins.

If One Were to Create a Single Antigen Vaccine to Have