A 22-year-old female student complains of excessive fatigue for the past 2 months. Polyarthralgia and vasculitis is noted on examination. Lab tests reveal multiple autoantibodies including antidouble-stranded DNA. The most logical diagnosis is

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These signs and symptoms are characteristic of lupus erythematosus, with antibodies to double-stranded DNA being selective for SLE. Although autoantibodies are present in Hashimoto's thyroiditis, anti-dsDNA is absent.

A 22-Year-Old Female Student Complains of Excessive Fatigue for the Past