Goodpasture's syndrome is characterized by glomerulonephritis in genetically susceptible individuals. The responsible antigen is

Question

Quizplus · Accepted Answer

In contrast to GLN in SLE (where circulating antigen-antibody complexes deposit randomly in the kidney in a lumpy bumpy pattern), the antigen in Goodpasture's syndrome is part of the glomerular basement membrane and its reaction with antibody produces a linear fluorescent pattern.

Goodpasture's Syndrome Is Characterized by Glomerulonephritis in Genetically Susceptible Individuals