People's Deliberate Use of Psychoactive Substances to Influence Behavior Dates

People's deliberate use of psychoactive substances to influence behavior dates from the

A) beginning of the 20th century, when recognition of the effects of alcohol led to the era of Prohibition.
B) middle of the 20th century, when chemical substances could first be synthesized from petroleum.
C) beginnings of humankind.
D) ancient Greeks, who became skilled at making wine.
E) late 20th century, when advances in biotechnology allowed the creation of drugs specifically designed to affect neurotransmitter systems.