When the malarial parasite invades a red blood cell, its metabolic waste products result in the acidification of the cytoplasm. Which of the following best describes the consequences of this acidification on the activity of hemoglobin (Hb) ?
A) formation of carbaminohemoglobin is enhanced
B) hemoglobin tetramers become less stable and the complex dissociates
C) there is a shift to a more R state conformation
D) there is a shift to a more T state conformation
E) there is no effect from the acidification
Correct Answer:
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