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You Are Treating an 11-Year-Old Female Type 1 Diabetic Patient

Question 3

Multiple Choice

You are treating an 11-year-old female type 1 diabetic patient who forgot to eat after she self-administered her afternoon insulin. Blood work demonstrates that her serum glucose level is 1 mM (18mg/dL) .
Which of the following statements correctly defines the metabolic situation in this patient?


A) a reversal of the muscle hexokinase reaction converts glucose 6-phosphate to glucose for oxidation in glycolysis
B) hepatic glycogen releases glucose in response to insulin-mediated dephosphorylation of glycogen phosphorylase
C) hepatic glycogen releases glucose through a reversal of the glycogen synthase reaction
D) phosphorylation of hepatic glycogen synthase prevents glucose incorporation into glycogen
E) the activity of muscle glycolysis is inhibited by the phosphorylation of PFK1

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