Patients with aldolase B gene mutations are required to avoid certain foods and products that contain fructose as their consumption can lead to significant hypoglycemia. In addition to fructose, consumption of which of the following carbohydrates must be avoided in these patients?

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Patients with aldolase B gene mutations have hereditary fructose intolerance. Sorbitol is a sugar alcohol that can be converted to fructose in the body, so it must be avoided.  Sorbitol is a sugar often used in the pharmaceutical and food industries as a thickener or for the production of transparent gels such as in certain toothpastes. Sorbitol can be metabolized to fructose via the action of sorbitol dehydrogenase. Therefore, it is important that patients with hereditary fructose intolerance monitor food and pharmaceuticals for the presence of sorbitol as ingestion can lead to significant health complications.

Patients with Aldolase B Gene Mutations Are Required to Avoid