In a study of the regulation of body weight, the administration of exogenous leptin to mice is found to increase the activity of proton leak channels located in the inner membrane of mitochondria in adipose tissue cells. Which of the following is most likely to increase as a result of the increased transport of protons through these mitochondrial leak channels?

Question

Quizplus · Accepted Answer

The increased activity of proton leak channels leads to a dissipation of the proton gradient across the mitochondrial membrane, resulting in increased heat production as energy is released as heat instead of being used for ATP synthesis.

In a Study of the Regulation of Body Weight, the Administration