You Are Investigating a Novel Series 1 Prostaglandin Inhibitor on the Activity

You are investigating a novel series 1 prostaglandin inhibitor on the activity of a section of femoral artery in culture. You have shown that the inhibitory compound directly interferes with the action of PGE
1) Which of the following activies is most likely reduced or absent in your organ culture system in the presence of this inhibitor?

A) activation of 5-LOX for leukotriene synthesis
B) enhancement of neutrophil adhesion
C) induction of slow cardiac contraction
D) platelet aggregation and activation
E) relaxation of vascular smooth muscle cells