In carrying out an assay using cultured hepatocytes you find that addition of hemin (Fe3+ heme) does not have the expected consequence of reduced protoporphyrin IX synthesis. This result suggests that your hepatocytes harbor a mutant form of one of the heme-regulated enzymes of porphyrin biosynthesis. Which of the following represents the likely enzyme?
A) ALA dehydratase
B) ALA synthase
C) ferrochelatase
D) heme oxygenase
E) PBG deaminase
Correct Answer:
Verified
Q1: A-18-year-old woman presented with 1-week of history
Q2: An 11-month-old male infant is presented with
Q4: A 32-year-old man has suffered from chronic
Q5: Acute intermittent porphyria (AIP) is the major
Q6: There is but a single enzyme-catalyzed reaction
Q7: A 9-month-old infant who suffered bouts of
Q8: An 18-month-old boy was referred to the
Q9: Which of the following represents the enzyme
Q10: An elderly homeless woman is brought to
Q11: A 37-year-old woman visits her primary care
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents