You are attending to a 47-year-old male patient who complains of chronic fatigue and persistent abdominal discomfort. Examination of the patient shows mildly icteric sclera and blood work indicates that serum bilirubin levels are 3 mg/dL. The bilirubin is predominantly unconjugated. The signs and symptoms in this patient are most likely due to which of the following disorders?

Question

Quizplus · Accepted Answer

Gilbert syndrome is a common, mild liver disorder where the liver doesn't properly process bilirubin, leading to mild unconjugated hyperbilirubinemia, which matches the patient's symptoms.  Gilbert syndrome is characterized by mild, chronic unconjugated hyperbilirubinemia. Almost all afflicted individuals have a degree of icteric discoloration in the eyes typical of jaundice. Serum bilirubin levels in Gilbert syndrome patients are usually less than 3 mg/dL. Many patients manifest with fatigue and abdominal discomfort. Presentation of Gilbert syndrome symptoms occurs more frequently in men than in women because the production of bilirubin is higher in men.

You Are Attending to a 47-Year-Old Male Patient Who Complains