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The Anticancer Drug Etoposide Functions Because It Inhibits the Activity

Question 28

Multiple Choice

The anticancer drug etoposide functions because it inhibits the activity of topoisomerase. Which of the following represents the normal function of this enzyme?


A) introduce the primer onto the template of DNA prior to replication
B) remove mismatched nucleotides at the end of replication
C) remove the RNA primer from each Okasaki fragment
D) stabilize single-stranded regions of DNA at the replication fork
E) unwind the DNA duplex during replication

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