You are studying the responses of adipocytes in culture to insulin following addition of a test compound. In the absence of the compound, addition of insulin to your culture system results in increased glucose uptake. However, following addition of the test compound, the effects of insulin on glucose uptake are severely impaired. Analysis of components of the insulin-signaling pathway indicates that addition of the compound results in a dramatic increase in O-GlcNAcylation. Your test compound is likely to be most highly related to which of the following?

Question

Quizplus · Accepted Answer

The Answer is B

You Are Studying the Responses of Adipocytes in Culture to Insulin