You are studying the gastric secretions of a patient swith a rare form of nutritional malabsorption. You discover that the defect is due to a near complete loss of secretion of pepsinogen into the stomach in response to food intake. These observations could be explained by a defect in which type of gastrointestinal secretory cell?

Question

Quizplus · Accepted Answer

Chief cells are responsible for secreting pepsinogen in the stomach. A defect in these cells would lead to a loss of pepsinogen secretion.  A gastric chief cell is a cell in the stomach that releases pepsinogen. Pepsinogen is activated into the digestive enzyme pepsin when it comes in contact with acid produced by gastric parietal cells.

You Are Studying the Gastric Secretions of a Patient Swith