Altered plasma renin levels can occur in both normal and pathologic conditions. Which of the following states is associated with a decrease in plasma renin levels?

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Primary aldosteronism is characterized by excessive production of aldosterone, leading to sodium retention, increased blood volume, and suppression of renin release, resulting in decreased plasma renin levels.  Most patients with primary aldosteronism (Conn syndrome) have an adrenal adenoma. The increased plasma aldosterone concentration leads to increased renal Na+ reabsorption, which results in plasma volume expansion. The increase in plasma volume suppresses renin release from the juxtaglomerular apparatus and these patients usually have low plasma renin levels. Secondary aldosteronism is due to elevated renin levels and may be caused by heart failure or renal artery stenosis.

Altered Plasma Renin Levels Can Occur in Both Normal and Pathologic