Which of the following regarding the differences between Hb and Mb is NOT correct?
A)Hb shows sigmoidal,whereas Mb shows hyperbolic oxygen saturation curves.
B)Hb shows cooperativity,whereas Mb does not.
C)Hb binds O₂ more tightly than Mb.
D)Hb-oxygen binding is dependent on physiological changes in pH,whereas Mb-oxygen binding is not.

Question

Quizplus · Accepted Answer

This statement is not correct. Mb binds O₂ more tightly than Hb. Hb is designed to pick up O₂ in the lungs, where the partial pressure of O₂ is high, and release it in the tissues, where the partial pressure of O₂ is lower. Mb, on the other hand, is found in the muscles and has a higher affinity for O₂, which allows it to hold onto O₂ and deliver it to the mitochondria for use in oxidative phosphorylation.

Which of the Following Regarding the Differences Between Hb and Mb