Which of the following is higher in thioesters than in oxygen esters?

Question

Quizplus · Accepted Answer

Thioesters have a higher group transfer potential than oxygen esters because sulfur is a weaker nucleophile than oxygen and therefore, the bond between the sulfur and the carbonyl carbon is more polarized towards the carbon, making it a better leaving group. This results in a higher energy of hydrolysis and a greater tendency for group transfer reactions. Electronegativity (A) and resonance (B) are not necessarily higher in thioesters than in oxygen esters, and positive ΔG (D) is not a characteristic that is specific to thioesters.

Which of the Following Is Higher in Thioesters Than in Oxygen