Which of the following enzymes,when genetically defective,can result in the most common form of hemolytic anemia?

Question

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Pyruvate kinase deficiency is the most common enzyme defect causing hemolytic anemia. Pyruvate kinase plays a critical role in glycolysis, which generates ATP in erythrocytes necessary for cell survival. Defective pyruvate kinase leads to a lack of ATP, resulting in hemolysis.

Which of the Following Enzymes,when Genetically Defective,can Result in the Most