Studies involving chronic PCP or ketamine administration to nonhuman primates and rodents have demonstrated all of the following neurobiological changes except

Question

Quizplus · Accepted Answer

Chronic administration of PCP or ketamine, which are NMDA receptor antagonists, does not lead to increased NMDA receptor binding in the prefrontal cortex. Instead, these substances are known to disrupt normal NMDA receptor function, which can lead to various neurobiological changes, but an increase in NMDA receptor binding is not one of them.

Studies Involving Chronic PCP or Ketamine Administration to Nonhuman Primates