Which statement about the role of the endogenous opioid system in alcohol's reinforcing effects is false?
A) Mice that lack the $\mu$-opioid receptor do not self-administer alcohol.
B) Opioid receptor antagonists reduce alcohol self-administration in animals.
C) Clinical trials show that opioid receptor antagonists decrease relapse to drinking in humans.
D) Chronic alcohol use increases gene expression of endorphin and enkephalin.

Question

Quizplus · Accepted Answer

The statement D is false because chronic alcohol use does not increase the gene expression of endorphin and enkephalin; rather, it can lead to adaptations in the endogenous opioid system that might contribute to dependence and addiction, but not necessarily through increased gene expression of these opioids.

Which Statement About the Role of the Endogenous Opioid System μ\muμ

Which Statement About the Role of the Endogenous Opioid System $\mu$