cAMP-dependent protein kinase phosphorylates and thus inhibits PFK-2.Which enzyme is simultaneously activated as a result of this inhibition?

Question

Quizplus · Accepted Answer

Inhibition of PFK-2 leads to a decrease in the concentration of fructose-2,6-bisphosphate (F-2,6-BP), which is a potent activator of phosphofructokinase-1 (PFK-1). However, the decrease in F-2,6-BP concentration also leads to the activation of fructose-2,6-bisphosphatase (F-2,6-BPase), which is responsible for the breakdown of F-2,6-BP. Therefore, choice D (F-2,6-BPase) is the best answer.

CAMP-Dependent Protein Kinase Phosphorylates and Thus Inhibits PFK-2