In a patient with diabetes,which of the following physiological changes is a result of increased glycosylation?

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Nonenzymatic glycosylation,or the chemical attachment of glucose to proteins without the involvement of enzymes,is known to affect fibrogen,collagen,antithrombin III,HDL,and LDL,all of which are involved in the evolution of CAD.The attachment of glucose to these molecules renders them less sensitive to the enzymes and other substances with which they interact.Thrombus formation enhanced via antithrombin III activity is decreased and fibrinogen is less likely to perform its function of degrading fibrin.

In a Patient with Diabetes,which of the Following Physiological Changes