Increased work of breathing and fatigue in a patient with asthma is BEST explained by which of the following physiological changes?

Question

Quizplus · Accepted Answer

Narrowing of peripheral airways results in premature closure,causing a marked increase in residual volume.The advantage of breathing higher lung volumes is that airways are held open and there is an increase in the elastic recoil of lungs,which increases the driving pressure of exhalation.However,at high thoracic volumes,the diaphragm and intercostal muscles must function over a suboptimal range of their length-tension curve,which increases the work of breathing and fatigue.

Increased Work of Breathing and Fatigue in a Patient with Asthma