A small Vd has an important influence on the half-life of a drug, this means that a drug with small Vd has short half-life.

Name: A small Vd has an important influence on the half-life of a drug, this means that a drug with small Vd has short half-life.
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Question

Quizplus · Accepted Answer

A small volume of distribution (Vd) means the drug is largely confined to the bloodstream, but the half-life also depends on clearance. A small Vd does not necessarily mean a short half-life if clearance is also low.

A Small Vd Has an Important Influence on the Half-Life