When fasting or eating a very-low-calorie diet for prolonged periods, the body will obtain fuel from its energy stores. One of the last reserves the body will use is

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When the body is in a state of prolonged fasting or very-low-calorie diet, one of the last energy reserves that the body will use is protein in muscle and organ tissue. The body will first use glycogen stores, followed by fat stores in the liver and subcutaneous fat, before breaking down muscle and organ tissue for energy. This can lead to muscle wasting and a decrease in organ function. It is important to maintain adequate protein intake during prolonged fasting or very-low-calorie diets to prevent this.

When Fasting or Eating a Very-Low-Calorie Diet for Prolonged Periods