A client has been taking oral anticoagulant therapy for a number of years secondary to atrial fibrillation. He asks about taking Ibuprofen to manage arthritic pain in his knees. What is a reason that Ibuprofen should be avoided?

Question

Quizplus · Accepted Answer

Rationale 1: Ibuprofen does not affect the actions of Vitamin K.
Rationale 2: Ibuprofen does not affect the actions of Vitamin K.
Rationale 3: Warfarin does not inhibit the anti-inflammatory actions of Ibuprofen.
Rationale 4: Extensive protein binding is responsible for numerous drug-drug interactions, some of which include NSAIDs, diuretics, selective serotonin reuptake inhibitors (SSRIs) and other antidepressants, steroids, antibiotics, vaccines, and vitamins (e.g., vitamin K). Concurrent use with NSAIDs may increase bleeding risk.

A Client Has Been Taking Oral Anticoagulant Therapy for a Number