In the function of the TCR, the purpose of the CD3 complex is to:
A) Bind antigen
B) Transduce signals
C) Anchor the TCR in the membrane
D) Stabilize the interaction between the TCR and the APC

Question

Quizplus · Accepted Answer

The CD3 complex is important for signal transduction because the TCR has only a short cytoplasmic tail that cannot carry the signal after binding of antigen. The CD3 complex does not interact with antigen during this process. The TCR has a hydrophobic transmembrane region that anchors the receptor in the membrane, and other markers, such as CD4 and CD8, serve to stabilize interactions between the TCR and APCs; the CD3 complex does not participate in these activities.

In the Function of the TCR, the Purpose of the CD3