The role that C3bBb3b plays in the complement pathway is to:
A) Cleave C2 to C2a and C2b
B) Cleave C3 to C3a and C3b
C) Cleave C4 to C4a and C4b
D) Cleave C5 to C5a and C5b

Question

Quizplus · Accepted Answer

C3bBb3b is the C5 convertase of the alternative pathway. Therefore, it cleaves C5 into C5a and C5b. C5a acts as a chemoattractant, and C5b is the first component in the membrane attack complex (MAC), which creates the pore in the cell surface of the pathogen.

The Role That C3bBb3b Plays in the Complement Pathway Is