Which of the following autoimmune disorders involves a complement defect?
A) Rheumatic fever
B) Goodpasture syndrome
C) Autoimmune hemolytic anemia
D) Systemic lupus erythematosus (SLE)

Question

Quizplus · Accepted Answer

Patients with SLE have reduced synthesis of some complement components, as well as defective receptors on macrophages. These defects results in ineffective removal of immune complexes, which deposit in tissues and cause significant damage, particularly to the kidneys.

Which of the Following Autoimmune Disorders Involves a Complement Defect