Patients have a high risk of losing all of their teeth due which disease?

Question

Quizplus · Accepted Answer

Papillion-Lefèvre syndrome is a rare autosomal recessive disorder characterized by destruction of bone, affecting both primary and secondary teeth, and hyperkeratosis, affecting the palms of the hands and soles of the feet. Germ-line mutation results in a loss of function in cathepsin C. Without cathepsin C, granzymes cannot be activated, and infected and tumor cells cannot be killed.

Patients Have a High Risk of Losing All of Their