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Omenn Syndrome Is an Immune Disorder Associated with Mutations in the Recombination-Activating

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Omenn syndrome is an immune disorder associated with mutations in the recombination-activating genes (RAG1 and RAG2) needed for gene switching in lymphocytes. What effect would this mutation have on B cells, T cells, and the overall health of the adaptive immune response?

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Gene switching occurs during the develop...

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