Insulin Is a Protein Made in Large Amounts in Cells

Insulin is a protein made in large amounts in cells of the pancreas.These cells secrete insulin into the blood,where it controls the uptake of sugar by body cells.How is insulin transported from the ER to the surface of the cell?

A) Insulin is sent through the cavities (lumen) of the endoplasmic reticulum that attach directly to the plasma membrane.
B) Insulin moves along tracks of cytoskeleton proteins.
C) Insulin moves through plasmodesmata to the surface of the cell.
D) Insulin is carried in small sacs of membrane (vesicles) that move from the endoplasmic reticulum to the Golgi apparatus and then to the plasma membrane.
E) Insulin is carried by lysosomes that empty their contents outside the cell.