The most common form of cystic fibrosis,a fatal genetic disease,occurs when a protein destined for the plasma membrane of the cell is destroyed.The protein is destroyed by one of the cell's organelles because the protein is not shaped correctly.Which organelle recognizes the misshaped protein?

Question

Quizplus · Accepted Answer

The rough endoplasmic reticulum is responsible for recognizing and fixing incorrectly folded or misshapen proteins. In cystic fibrosis, a mutation in the CFTR gene results in the production of a faulty CFTR protein that is incorrectly folded and processed in the rough endoplasmic reticulum, leading to its degradation before it can reach the cell membrane.

The Most Common Form of Cystic Fibrosis,a Fatal Genetic Disease,occurs