How does primary protein structure affect the function of protein enzymes?

Question

Quizplus · Accepted Answer

The primary protein structure determines the specific sequence of amino acids, which in turn determines the three-dimensional structure of the protein. The R-groups (side chains) of the amino acids at the active site of enzymes interact with substrates through various chemical reactions such as bonding, steric interactions, and charge-charge interactions in order to catalyze a specific chemical reaction. Therefore, the primary protein structure affects the function of protein enzymes by determining the arrangement of amino acids and R-groups at the active site, which directly interacts with substrates.

How Does Primary Protein Structure Affect the Function of Protein