Ovalbumin,the major protein of egg white,is secreted by cells that line the oviduct as the bird egg moves down the oviduct.Imagine you're repeating the classic Weintraub-Groudine experiment,but with a twist:
You're assaying the DNase sensitivity of the promoter regions of the β-globin and ovalbumin genes in oviduct cells of laying hens.In this case you expect to find that _____.
A)the β-globin and ovalbumin promoters are equally sensitive to DNase treatment
B)the β-globin and ovalbumin promoters are equally resistant to DNase treatment
C)the β-globin promoter is much more sensitive to DNase treatment
D)the ovalbumin promoter is much more sensitive to DNase treatment

Question

Quizplus · Accepted Answer

Since ovalbumin is secreted by cells lining the oviduct, and hens lay eggs, it is likely that the ovalbumin gene is specifically expressed in oviduct cells. Therefore, the promoter region of the ovalbumin gene is expected to be more accessible to DNase treatment compared to the β-globin gene promoter, which is expressed in a variety of cell types. Thus, the answer is D, the ovalbumin promoter is much more sensitive to DNase treatment.

Ovalbumin,the Major Protein of Egg White,is Secreted by Cells That