Use the Following Information When Answering the Corresponding Question(s)

Use the following information when answering the corresponding question(s) .
Researchers found that high doses of nitric oxide were not lethal to soybean cells.Likewise,high doses of reactive oxygen intermediates were not lethal to soybean cells.However,when combined,nitric oxide and reactive oxygen intermediates were very lethal to soybean cells.(M.Delledonne et al.2001.Signal interactions between nitric oxide and reactive oxygen intermediates in the plant hypersensitive response.Proceedings of the National Academy of Sciences,USA 98(23) :13454-59. )
-Refer to the paragraph on Delledonne et al.Based on the findings presented in the paragraph,combined with what you have learned about the hypersensitive response,which sequence of events occurs when a pathogen infects a plant cell? (Only some of the events will be used. )
1) The R protein binds to the avr protein.
2) The pathogen releases avr proteins.
3) The plant cell produces nitric oxide.
4) The pathogen produces reactive oxygen intermediates.
5) A signal transduction cascade occurs.
6) The plant cell and the pathogen die.
7) The pathogen dies,the plant cell lives.
8) The plant cell produces both nitric oxide and reactive oxygen intermediates.

A) 1,5,8,2,7
B) 2,1,5,8,6
C) 2,3,4,5,7
D) 2,5,4,3,6
E) 1,5,4,3,7