How could you increase the magnitude of inhibitory postsynaptic potentials (IPSPs)generated at a synapse?
A)increase sodium-potassium pump activity
B)increase K⁺ permeability
C)increase the influx of calcium
D)All of the above apply.

Question

Quizplus · Accepted Answer

Increasing K⁺ permeability would cause more K⁺ ions to leave the cell, hyperpolarizing the membrane potential further and increasing the magnitude of IPSPs. Increasing sodium-potassium pump activity would not affect the magnitude of IPSPs. Increasing the influx of calcium would actually decrease the magnitude of IPSPs by facilitating the release of excitatory neurotransmitters.

How Could You Increase the Magnitude of Inhibitory Postsynaptic Potentials