Match the tentative interpretation of antibody screen and direct antiglobulin test (DAT) with the results given below.
-Both screening cells 2+ at antihuman globulin phase, DAT positive, IgG 2+

Question

Quizplus · Accepted Answer

The positive direct antiglobulin test (DAT) suggests the presence of antibodies coating red blood cells, which could be due to an autoantibody or a transfusion reaction. The presence of IgG further supports an immune-mediated reaction rather than a non-specific reaction like rouleaux formation. The fact that both screening cells are positive at the antihuman globulin phase suggests the antibodies are directed against a common antigen on both cells, which is more consistent with an alloantibody rather than an autoantibody. Therefore, the most likely interpretation is a transfusion reaction due to alloantibodies, although an autoantibody cannot be completely ruled out.

Match the Tentative Interpretation of Antibody Screen and Direct Antiglobulin