Production of exotoxin A, which kills host cells by inhibiting protein synthesis, and production of several proteolytic enzymes and hemolysins that destroy cells and tissue are factors that contribute to pathogenicity of

Question

Quizplus · Accepted Answer

Although Pseudomonas aeruginosa is an environmental inhabitant, it is also a very successful opportunistic pathogen. Factors that contribute to pathogenicity include production of exotoxin A, which kills host cells by inhibiting protein synthesis, and production of several proteolytic enzymes and hemolysins that destroy cells and tissue. On the bacterial cell surface, pili may mediate attachment to host cells. Some strains produce alginate, a polysaccharide polymer that inhibits phagocytosis and contributes to infection potential in patients with cystic fibrosis.

Production of Exotoxin A, Which Kills Host Cells by Inhibiting