What is the expected result when two homologous chromosomes fail to separate during meiosis I of spermatogenesis?
A)Fertilization of this gamete may result in a zygote that is 48, XXYY.
B)One gamete will have two of these chromosomes, and one will have neither of these chromosomes.
C)The risk for development of polygenic disorders is increased with fertilization of the polar body associated with this mature gamete.
D)Increased genetic diversity is possible with fertilization of any of these four gametes because of an increased number of possible gene alleles.

Question

Quizplus · Accepted Answer

Failure of a chromosome to separate properly during meiosis is nondisjunction. The result of nondisjunction is that one cell will have two copies of the chromosome, and the other cell will not have a copy of this chromosome. Depending on which chromosome is missing or present in two copies, viable embryos may be produced from fertilization, either as monosomies or trisomies. This process does not result in a zygote with 48 chromosomes, nor will genetic diversity be increased. Polar bodies do not form in spermatogenesis.

What Is the Expected Result When Two Homologous Chromosomes Fail