Which statement is a criterion for an autosomal-dominant pattern of inheritance of a specific trait or characteristic that is highly penetrant?
A)Carriers for the trait may express it but do not necessarily express the trait.
B)Unaffected family members do not transmit the trait to their children.
C)Genotypes of individuals expressing the trait must be homozygous.
D)The trait appears only among male offspring of female carriers.

Question

Quizplus · Accepted Answer

A highly penetrant autosomal-dominant gene is expressed close to 100% of the time and can be expressed in the homozygous or heterozygous genotype. Thus, only family members who do not express the trait or characteristic do not have the allele and cannot transmit it to their offspring. An autosomal-dominant gene is expressed equally among males and females.

Which Statement Is a Criterion for an Autosomal-Dominant Pattern of Inheritance